| 1 | Spider-Man: Across the Spider-Verse | 2023-05-31 | $100M | $398.94M | 3.99 |
| 2 | Deadpool | 2016-02-09 | $58M | $375.74M | 6.48 |
| 3 | Deadpool 2 | 2018-05-10 | $110M | $343.06M | 3.12 |
| 4 | Logan | 2017-02-28 | $97M | $235.76M | 2.43 |
| 5 | Venom | 2018-09-28 | $116M | $223.51M | 1.93 |
| 6 | Spider-Man: Into the Spider-Verse | 2018-12-06 | $90M | $193.67M | 2.15 |
| 7 | X-Men: Apocalypse | 2016-05-18 | $178M | $163.35M | 0.92 |
| 8 | Dark Phoenix | 2019-06-05 | $200M | $70.85M | 0.35 |
| 9 | Fantastic Four | 2015-08-05 | $120M | $58.75M | 0.49 |
| 10 | The New Mutants | 2020-04-02 | $67M | $24.61M | 0.37 |
| 11 | The Amazing Spider-Man | 2012-06-23 | $215M | $686.56K | 0.00 |
| 12 | The Amazing Spider-Man 2 | 2014-04-16 | $200M | $676.41K | 0.00 |